Steroids

How Do American Swimmers Manage to Trash Cheating Scumbags Without Steroids?

Published

6 years ago

December 3, 2018

Paul

Steroid Use By Swimmers:

Steroid Use By Swimmers

Androgenic Steroids improve performance by increasing tissue mass. These also help in carrying more oxygen through blood cells and also enhance nerve induction or signaling. A trained individual gets more benefit out of any pattern or therapy, and the same is evident for the American swimmers.

Anabolic Steroids:

Anabolic Steroids

These resemble male sex dihydrotestosterone and testosterone hormones. These are male hormones that play a role in strengthening men’s body as compared to women. Exogenous steroids use allows fast recovery and increases in muscle protein development; thus, fast muscle building makes you stronger.

They have chronic toxicity due to constant use like high blood pressure, premature balding, dyslipidemia, acne, infertility, and other sex associated illnesses.

The problem comes with its use in sports; Anti-Doping World Authority has banned steroids in supports. So the point comes how the swimmers can beat anti-doping tests or blood tests and what other options can consider. They go for alternative options and selective doses to maintain the proper muscle mass to ease swimming and electric mobility in water. Swimmers need a high level of red blood cells with high oxygen-carrying that can make the player win efficiently.

Research shows Testosterone at doses below 160 mg/ml a week can be disguised. In sports, cheating does not just limit to steroids; there are also other modes employed by the players that are also very difficult to detect.

Facts:

Usually, steroids used by players, and for fasten recovery, PCT considered. Oral and injectable steroids such as Dianabol and Anabol allowed users to win several sports. Overall the practice is hazardous, and therefore the steroid use is also banned. Swimmers use “EPO” variations to increase RBCs count to enhance their body aerobic activity.
Steroids use less beneficial for swimmers, and they have to switch to other options to get the top winning position.
Swimmers also look for endurance, injury prevention, strength, confidence, and recovery.

Sports history depicts that steroids improved swimming speed, but the problem is their detection that has limited their usage, as EPO drug users were caught cheating. The USA implemented high restrictions while foreign swimmers observed with another scenario where coaches have been found involved in doping practice to place their athletes at winning edge for their financial gain.

The past ages were the stories when athletes had won without any performance enhancers; now the masked PED's and other modified versions that cannot be diagnosed are used.

Performance Enhancing and Anti-Doping Products:

Synthetic erythropoietin or (EPO), Carbohydrates, and many other drugs used for performance enhancement.

Carbohydrates as Performance Enhancers:

Carbohydrates are macronutrients just like fat and protein, and the unique characteristic of starch is that we can consume it under lower oxygen environment or anaerobic conditions. During high exertion levels, the process of oxygen transfer to cells for oxidation slows down, and carbohydrates become the energy source.

It means that anaerobic activity can be carried out without eating carbohydrates. When you take fats and protein, they generate glycogen that muscles utilize during oxygen deprivation period. Carbohydrates make muscle fat and enhance athletic physical realization. Nutritional ketosis is associated with adverse health impacts that (1)hinders the physical performance and results (2)in a reduction of dietary carbohydrates to <50 grams/day. So, nutrition is an essential, and nutritional plan is a significant concern in this regard. Carbohydrates dietary intake can be considered for performance-enhancing. Better drugs that are legal to use and better options can lead to a massive gain in health and sports areas. These are legal while anabolic steroids in sports, but also does not allow legally for athletes to use them. We can see the example of alcohol and cigarettes both are legal while marijuana is illegal. Carbohydrate consumption also associated with some side effects like higher levels cause insulin resistance, obesity, metabolic problems, diabetes, Alzheimer’s disease, and cancer.

Efamol EPO, 1000:

The kidney produces Erythropoietin (EPO) hormone that maintains hemoglobin RBCs production. These cells carry oxygen to the body organs and bring carbon dioxide in exchange that removes through the lungs. RBCs carry Hemoglobin protein that performs the function of oxygen binding and carbon dioxide removal. In case of any injury or blood donation, kidneys produce more EPO that results in more RBCs manufacturing in the bone marrow.

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Blood Doping:

Blood Doping

Athletes do this practice; they take out 10 to 2o % of their body blood and store a few months ago before the competition. Kidney diagnoses it, and the body produces natural EPO to attain an average hemoglobin level. Just before the tournament, player re-injects the previously drawn RBCs that build high levels of the protein hemoglobin. That was the old practice; now, synthetic EPO is available that offer similar results.

EPO Benefits:

Swimming is high energy-requiring an exhaustive activity that requires high oxygen retention capacity of RBCs. Limited capacity will result in more fatigue and will imbalance the player stamina in limited time. Synthetic EPO boosts the RBCs numbers and thus associated activity that meets the player’s expectation.

Risks:

They raise the RBC level above the 15 to 16 g/dL that also happens in few disease conditions. High viscosity blood increases blood clotting risk, myocardial infarction or heart attack, pulmonary embolism, and stroke that are fatal situations. These areas require more research to determine the exact number of disease incidences in population and also the ways to avoid the severity.

Commonness between steroids, EPO and carbohydrates

The similarity between anabolic steroids, sugars, and EPO is that all three enhances athlete performance.
All these are good for starters, and their effects or side effects vary individually depending on dose levels and genetic factors.
Regulations and drug testing are obstacles in anabolic steroids use, EPO, and carbohydrates. These supplemental components are now mandatory to get what targeted. Yes, that is THE Victory!

EPO product Description:

EPO Drug:

EPO/ erythropoietin can inject to enhance athlete performance. Kidney cells naturally produce the protein, and kidney cells also detect oxygen levels deficiency in the bloodstream. EPO use enhances oxygen absorption, RBCs production, reduce fatigue, and it also increases the rate of metabolism and muscles healing.

Is EPO Steroid?

EPO is a hormone, and its use in the Olympics is illegal or banned. So, it is not precisely the steroid.

Is Carbohydrate Steroid?

Carbohydrates classify as legal. These are not a steroid, these obtained from the diet and oral pills can also take after medical consultation.

Erythropoietin Intense Levels:

Low level of natural erythropoietin gives rise to kidney diseases or anemia that is kidney failure. Synthetic Erythropoietin treats such problems, while sport’s men take it to boost their performance level. High intensity associated with severe risks to particular body organ such as heart muscle, liver, and lungs

Types of Blood Doping

The most widely used blood doping types are:

Blood transfusions
Erythropoietin (EPO) injections
Oxygen synthetic carrier injections

Blood transfusions: It is carried in treating conditions like injuries, blood deficiency, etc.

Athletes also do it illegally for a performance boost. It may be autologous transfusion or homologous transfusion.

Autologous transfusion involves the athlete's body blood that is taken out and stored to use in the future. While in Homologous transfusion, the blood of other person having similar group taken for the purpose.

- EPO injections involve syringe used to inject the dose in the body muscle.

- Oxygen Synthetic carriers are chemicals with the ability to transfer oxygen. These are used in medical fields to rescue the patient in the case when

Human blood seems unavailable
Or due to the contamination issues

Athletes use it for performance-enhancing.

Recombinant Erythropoietin

Nowadays, recombinant erythropoietin synthetically produced. It is a synthetic natural erythropoietin version that stimulates erythropoietin agents that further produces RBCs. Its purpose is to beat the tests and body complications.

All blood doping practices enhance RBCs numbers in the body. It involves the illegal products use such as erythropoietin (EPO), HIF stabilizers, and darbepoetin-alfa to increase oxygen absorption by cells. Oxygen uptake depends directly on cells oxygen extraction, cardiac output, and hemoglobin mass.

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Hypoxia-Inducible (HIF) Stabilizer Factor:

This HIF stabilizer, used for kidney disease treatment. This HIF stabilizer activates EPO. These HIF stabilizers with cobalt chloride or desferrioxamine used by the athletes to either stimulate and stopping the erythropoietin hormone production in the body. Later, the body itself decays or naturally removes this substance.

Trispyrophosphate Myo-Inositol:

This compound is the current research subject in the field of anti-doping for athletes in different areas, swimming, cycling, etc.

Cobalt Chloride:

It is a metal complex and inorganic in nature that is also considered necessary in the process of blood doping. Cobalt complex used for the dietary supplement as Cobalamin develops RBCs. However, it yields very mild results, while Cobalt (II) chloride yields fast and better results as compared to a pure compound.

But, some methods are given by the sports authorities to detect even the presence of such mineral complexes. Athletes use such variants and new or emerging varieties of compounds developed in laboratories with mask effects to beat the doping tests.

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Steroids

Decoding IGF-1 LR3: A Guide to its Benefits

Published

2 weeks ago

April 25, 2025

Sane

IGF-1 LR3 (Insulin-like Growth Factor-1 Long Arg3) is a synthetic variant of IGF-1, a hormone produced by the liver in response to growth hormone (GH). Unlike GH, which works indirectly, IGF-1 directly facilitates the growth and repair of muscle cells.

Related Article: Ostarine for Beginners; The Ultimate Guide

This modified version of IGF-1 is engineered to avoid binding with IGF-binding proteins, extending its half-life to 20–30 hours. As a result, it remains active in the body significantly longer than natural IGF-1.

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Many performance athletes incorporate IGF-1 LR3 post-workout to enhance muscle growth, speed up recovery, and support fat loss. When injected into specific muscle groups, it often produces localized effects. Additionally, it helps with nutrient distribution and, in some cases, improves insulin sensitivity.

On the other hand, human growth hormone (HGH) operates more broadly and indirectly, stimulating the liver to produce IGF-1 and offering more systemic benefits such as improved skin health, joint support, and fat reduction, albeit at a slower pace.

Typical IGF-1 LR3 doses range from 20–50 mcg daily, administered subcutaneously or intramuscularly, often following a workout.

Key Features of IGF-1 LR3

Enhanced Bioavailability: It avoids binding with IGF-binding proteins, increasing its potency.

Muscle Growth & Repair: Directly stimulates muscle cell proliferation and differentiation.

Improved Nutrient Distribution: Helps shuttle nutrients into muscle cells, supporting recovery.

Potential Fat Loss Benefits: Some users report improved insulin sensitivity and fat metabolism.

Mechanism of Action

IGF-1 LR3 interacts with IGF-1 receptors on muscle cells, activating pathways like PI3K-AKT and MAPK, which are crucial for cell growth and regeneration. This makes it a powerful tool for bodybuilders and athletes looking to optimize recovery and muscle development.

What Are the Top 10 Alternatives to IGF-1 LR3?

Here are some of the top alternatives to IGF-1 LR3, each with unique benefits for muscle growth, recovery, and performance:

BPC-157 – Known for its regenerative properties, it enhances healing and tissue repair.

CJC-1295 – A growth hormone-releasing peptide that boosts GH levels for muscle development.

Ipamorelin – Stimulates GH release with minimal side effects, making it a safer option.

MK-677 (Ibutamoren) – A potent GH secretagogue that promotes muscle growth and fat loss.

Sermorelin – Encourages natural GH production, supporting recovery and lean muscle gains.

Tesamorelin – Primarily used for fat loss, but also aids in muscle preservation.

Follistatin-344 – Inhibits myostatin, allowing for increased muscle hypertrophy.

PEG-MGF (Pegylated Mechano Growth Factor) – Enhances muscle repair and growth post-exercise.

GHRP-6 – Stimulates appetite and GH release, supporting muscle mass gains.

GHRP-2 – Similar to GHRP-6 but with fewer hunger-related side effects.

Each of these peptides has distinct mechanisms and benefits.

Must Read: Are Nootropics a Better Option to AAS?

Potential Risks Associated With IGF-1 LR3

IGF-1 LR3 comes with several potential risks, especially for bodybuilders using it to enhance muscle growth. Here are some key concerns:

Hypoglycemia (Low Blood Sugar) – IGF-1 LR3 increases glucose uptake in muscle cells, which can lead to dangerously low blood sugar levels if not managed properly.

Organ Growth – Since IGF-1 affects all tissues, excessive use may lead to unwanted growth in organs, increasing health risks.

Cancer Risk – IGF-1 plays a role in cell proliferation, and elevated levels have been linked to an increased risk of certain cancers.

Water Retention & Edema – Some users experience bloating and fluid retention, which can affect performance and aesthetics.

Joint Pain & Stiffness – Excessive IGF-1 levels may contribute to joint discomfort due to increased tissue growth.

Cardiovascular Issues – There is some concern that IGF-1 LR3 could contribute to heart enlargement or other cardiovascular complications.

Desensitization – Long-term use may reduce the body's natural IGF-1 production, leading to dependency

Overall

IGF-1 LR3's ability to bypass IGF-binding proteins makes it more potent but also increases the likelihood of desensitization with prolonged use. For those considering it, careful dosing and monitoring are crucial to mitigate side effects.

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Steroids

AOD-9604: The Fat-Burning Peptide Explained

Published

1 month ago

April 9, 2025

Sane

AOD-9604, along with the similar HGH Frag 176-191, is a peptide derived from Growth Hormone that includes only the amino acids in HGH responsible for stimulating fat breakdown, known as lipolysis.

This means that these peptides offer the fat-burning benefits of HGH without its other effects—whether beneficial or adverse—and come at a lower cost.

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Lipolysis refers to the process where fat cells are broken down to be utilized as energy. AOD-9604 promotes accelerated fat loss by increasing the body's use of fat as fuel.

For optimal results, the peptides should be used in a fasted state. AOD-9604 and Frag 176-191 are most effective when administered at a dose of 125-250mcg before bedtime (at least 3-4 hours after eating) and in the morning at the same dose, followed by a fasting period of 3-4 hours, ideally combined with fasted cardio.

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Similar Peptides with Fat-Burning Effect

Here’s a list of 10 peptides similar to AOD-9604, each with a brief description:

Ipamorelin: A growth hormone-releasing peptide (GHRP) that stimulates the natural release of growth hormone, promoting fat loss, muscle growth, and improved recovery without affecting other hormones like cortisol or prolactin.

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CJC-1295: A peptide that increases growth hormone and IGF-1 levels, aiding in fat loss, muscle gain, and improved sleep quality. It has a long half-life, making it convenient for users.

HGH Frag 176-191: A fragment of human growth hormone specifically designed for fat-burning. It targets adipose tissue without the broader effects of full-length HGH.

Tesamorelin: Known for reducing visceral fat, this peptide stimulates the release of growth hormone and is often used for weight management and metabolic health.

BPC-157: While primarily known for healing and recovery, BPC-157 can support fat loss indirectly by improving gut health and reducing inflammation.

Melanotan II: Originally developed for skin tanning, it also has appetite-suppressing properties, making it useful for weight management.

Thymosin Beta-4 (TB-500): Focused on healing and recovery, it can enhance physical performance and indirectly support fat loss through improved activity levels.

GHRP-6: A growth hormone-releasing peptide that boosts appetite and metabolism, aiding in muscle growth and fat loss.

Semaglutide: A GLP-1 receptor agonist that regulates appetite and blood sugar levels, making it effective for weight loss and metabolic health.

MK-677 (Ibutamoren): A growth hormone secretagogue that increases growth hormone and IGF-1 levels, promoting fat loss, muscle gain, and improved recovery.

List of Peptides With a Counteractive Effect Bodybuilders Must Avoid

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Some peptides can inadvertently lead to fat gain due to their effects on metabolism and appetite regulation. Here are a few that bodybuilders might want to avoid or use cautiously:

GHRP-6 – While it stimulates growth hormone release, it also significantly increases appetite, which can lead to excess calorie consumption and fat gain.
IGF-1 LR3 – This peptide enhances muscle growth but can also promote fat storage if not carefully managed with diet and training.
MK-677 (Ibutamoren) – Though technically a growth hormone secretagogue rather than a peptide, it boosts GH levels but often leads to increased hunger and potential fat accumulation.
CJC-1295 with DAC – While effective for muscle growth, its prolonged GH release can sometimes lead to unwanted fat retention if not paired with a strict diet

Overall

AOD-9604, derived from Growth Hormone, stimulates fat-burning by targeting lipolysis—the breakdown of fat for energy. It delivers these benefits without the additional effects of Growth Hormone, making it more cost-effective. For maximum effectiveness, it should be administered in a fasted state, ideally before bed and again in the morning at 125-250mcg doses. Pairing its use with fasting and fasted cardio can further enhance fat loss. Its sole focus is on improving the body’s ability to burn fat efficiently.

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Bodybuilding

Understanding Trenbolone-Induced Cough (“Tren Cough”)

Published

1 month ago

April 7, 2025

Sane

Trenbolone, a potent anabolic steroid, can sometimes cause “tren cough”—a sudden and intense coughing episode shortly after injection. Although not exclusive to Trenbolone, it is more commonly associated with this substance due to its highly irritant nature.

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Mechanisms Behind Tren Cough

Solvent and Carrier Irritation

Trenbolone formulations often include volatile solvents like benzyl alcohol or benzyl benzoate, which may irritate lung tissues when absorbed quickly into systemic circulation.

Prostaglandin Release

Trenbolone promotes increased production of prostaglandins, particularly PGF2α. This compound triggers contraction in the smooth muscles of the lungs, leading to bronchoconstriction and coughing.

Micro-Oil Embolism

Tiny oil droplets from an injection can reach capillaries and travel to the lungs, causing mild embolic reactions that lead to temporary oxygen deprivation and coughing.

Histamine and Mast Cell Activation

For some individuals, Trenbolone triggers histamine release and mast cell activation, mimicking an allergic response and causing bronchospasms and cough reflexes.

Related Article: Best Syringes for Steroid Injection on Amazon

Using Salbutamol (Albuterol) to Manage Tren Cough

Salbutamol, a widely-used β2-adrenergic receptor agonist, can alleviate tren cough symptoms by:
Relaxing bronchial muscles, easing spasms that cause coughing.
Inhibiting prostaglandin effects, reducing bronchoconstriction associated with PGF2α.
Opening airways, preventing severe respiratory restrictions in susceptible individuals.

Application Methods

Inhaler (Optimal)

Take 1–2 puffs of salbutamol (100–200 mcg) 5–10 minutes before a Trenbolone injection. If coughing occurs afterward, additional puffs can swiftly resolve the issue.

Oral Tablets (Moderate)

Consuming 2–4 mg tablets 30–60 minutes before injection offers slower, longer-lasting relief but may be less effective than inhalation methods.

Nebulizer (Severe Cases)

For individuals with frequent episodes, nebulized doses of 2.5 mg salbutamol can provide substantial relief.

Preventive Measures to Reduce Tren Cough Risk

Inject slowly to minimize systemic absorption and irritant effects.
Split doses to lower reaction severity with smaller quantities.
Opt for ventrogluteal injection sites, which have fewer blood vessels, reducing oil embolism risk.
Choose lower-concentration solutions to lessen irritation, as higher concentrations (e.g., Tren Ace 200 mg/ml) are more likely to provoke reactions.

What Other Steroids Can Induce Coughing?

Here's a curated list of peptides, SARMs, and PEDs that may potentially cause coughing or respiratory irritation in bodybuilders and fitness enthusiasts:

Peptides

IGF-1 LR3 (Insulin-like Growth Factor): Known for its anabolic effects, IGF-1 LR3 can occasionally cause mild respiratory irritation due to systemic absorption.

TB-500 (Thymosin Beta-4): While rare, improper injection techniques or high doses may lead to transient coughing episodes.

GHRP-6 (Growth Hormone-Releasing Peptide): This peptide can stimulate histamine release, potentially leading to bronchospasms and coughing.

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SARMs (Selective Androgen Receptor Modulators)

RAD-140: (Testolone) Some users report throat irritation or coughing, often attributed to solvents used in liquid formulations.

YK-11: Known for its myostatin-inhibiting properties, YK-11 may cause mild respiratory discomfort in sensitive individuals.

LGD-4033 (Ligandrol): Though uncommon, some users experience coughing due to carrier solvents or allergic-like reactions.

PEDs (Performance-Enhancing Drugs)

Boldenone Undecylenate (Equipoise): This injectable steroid can cause “Equipoise cough,” similar to tren cough, due to oil embolism or irritant solvents.

Testosterone Suspension: The water-based formulation may lead to coughing episodes if injected improperly or absorbed rapidly.

Nandrolone Decanoate (Deca-Durabolin): While less common, coughing can occur due to histamine release or systemic irritation.

More Tips to Minimize Coughing Risks

Use proper injection techniques to avoid embolic reactions.
Opt for lower-concentration solutions to reduce irritant effects.
Consider antihistamines or bronchodilators for individuals prone to respiratory sensitivity.

Are There Alternatives to Cough-inducing Steroids?

Here are some alternatives to cough-inducing steroids that can provide similar anabolic effects while minimizing respiratory irritation:

Peptides

IGF-1 LR3 (Insulin-like Growth Factor)

Promotes muscle growth and recovery without the irritant properties of certain steroids.

TB-500 (Thymosin Beta-4)

Enhances tissue repair and reduces inflammation, making it a safer option for recovery.

BPC-157 (Body Protection Compound)

Known for its healing properties, it supports muscle repair and joint health.

SARMs (Selective Androgen Receptor Modulators)

RAD-140 (Testolone)

Provides significant muscle-building effects with fewer systemic side effects compared to traditional steroids.

LGD-4033 (Ligandrol)

Boosts lean muscle mass and strength without the risk of respiratory irritation.

MK-677 (Ibutamoren)

Stimulates growth hormone release, aiding in muscle growth and recovery.

Natural Alternatives

Turkesterone

A plant-based ecdysteroid that supports muscle protein synthesis and recovery.

Ecdysterone

Another natural compound that mimics anabolic effects without the harsh side effects.

Creatine Monohydrate

Enhances strength and muscle mass through improved energy production during workouts.

Other Options

Human Growth Hormone (HGH)

Promotes muscle growth and fat loss, though it requires careful monitoring due to potential side effects.

Testosterone Boosters

Natural supplements like D-Aspartic Acid or Tribulus Terrestris can help optimize testosterone levels for muscle growth.

SARMs Alternatives

Legal and safer versions of SARMs are available, offering similar benefits without the risks associated with traditional SARMs.

Overall

We have explored the phenomenon of "tren cough," a sudden, intense coughing episode often caused by Trenbolone injections due to factors like solvent irritation, prostaglandin release, micro-oil embolism, or histamine activation. Preventive measures such as using salbutamol (via inhaler, oral tablets, or nebulizer), injecting slowly, splitting doses, and opting for lower-concentration solutions were highlighted.

Additionally, alternative compounds to tren cough-inducing steroids were discussed, including peptides like IGF-1 LR3 and TB-500, SARMs such as RAD-140 and LGD-4033, and natural options like Turkesterone, ecdysterone, and creatine. These alternatives provide anabolic effects while minimizing respiratory side effects. The conversation also underscored the importance of proper injection techniques and thoughtful compound selection to reduce risks.

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