Steroids

Oral and Injectable Steroids

Published

13 years ago

August 3, 2012

F Kyle

Surely that all bodybuilders know that anabolic steroids have two forms of administration, namely oral and injectable. Both of them have pluses and minuses which we will analyze in this article. Let’s see the specific or oral steroids. Oral steroids have a narrow range of assortment, their number can be counted on fingers. Of course, the most popular of them is well-known Metal and all its analogs like Dianabol, Nerobolum and many others.

Also to this list belongs to another form of the oral steroid called Winstrol/ Stanazolol/Stromba and Primobolan. Add to this list Oximetalon and Andriol capsules and you have here almost all oral steroids. So, let’s describe briefly what are oral steroids. It is known that a simple testosterone cannot be absorbed orally, it is destroyed in the stomach and intestines without having absorbed into the blood. It's been checked hundreds of experiments on the athlete.

Why have been done so many experiments on testosterone? In women is more easily to determine the level of increase of male sex hormones in the blood. This being said, we know that in a man's sperm along with the seminal fluid and sperm is released yet a number of male sex hormone testosterone.

That’s why sports physicians propose athletes immediately before the performance drink this liquid for the sharp rise of the level of hormones in the blood. For this purpose, to the competition have been driven donor men with a great opportunity to allocate sperm. Ok, the way athletes get this liquid is unknown, we can only suppose it, but the truth is that method proved to be useless.

Must Read: Steroids and Sporting Society

All oral steroids are designed at the molecular level so that they are not destroyed in the gut entirely, but are absorbed into the blood. At the same time, the blood passes through the cleaning cycle through the liver, which is the main filter of the body, where the lion's share of the drug is activated.

This is the main cause of death of liver cells as a result of oral steroids use. Many physicians propose to take this type of medication orally keeping it under the tongue, bypassing the stage of purification of blood by the liver. But this method is proved to be uncomfortable and painful.

Related Article: Liver Damage While On Oral Steroids

Oral and Injectable Steroids

Try to walk for about fifteen minutes after the complete dissolution of the tablet under the tongue with a mouth full of nasty saliva. Surely you will not like it, and you will abandon this method after several attempts. Of course, the oral preparations are very convenient to use. Usually, they are chosen by people who are afraid of injections and would never replace this form of steroids.

Another plus, and minus simultaneously of oral medications is that they have a short influence and are rapidly destroyed in the liver and blood. The lifetime of oral steroids is up to 24 hours. For this reason, this type of drugs is used in equal portions during the day to maintain the proper level of hormones in the blood.

Oral steroids are very convenient for athletes who face the competition doping control since oral medications are fast acting and leave the body. So, depending on your body after taking chemistry in 5-10 days, no test can detect in your urine or blood metabolites and hormones themselves.

Also, in the conclusion of this group of steroids have to be mentioned that as a rule, the same steroid in the injectable or oral form in the same dosage differ in strength and duration. Hence according to the opinions of many athletes, the oral form of steroids is weaker than a similar injection. And that, in general, it is logical, because the chemistry of drugs acting differently.

So, Summarizing The Above we Have:

Summarizing

Oral forms of steroids are toxic to the liver, in contrast to their injecting counterparts.
Oral steroids have a very short period, causing a sharp rise and fall of hormone levels in the blood.
Pills have to be taken on the same portions during the day.
Oral steroids are rapidly eliminated from the body. Just a week and you are pure as glass.
This type of steroid is preferred by novices athletes or people who are afraid of injections.

The second one group of steroids is injectable steroids. This group of drugs is the antipode of oral steroids in the majority. Firstly, the range of injectable steroids is much wider and more diverse. Among injectable steroids have to be mentioned Winstrol which is different from all other forms of injectable steroids.

Must Read: Stacking Dianabol with Injectable Steroids

So, if you take some capsules with any anabolic steroids, then you will not notice any fundamental difference to the smell or the light. Why are these mixture so popular worldwide? You have to know that in order for a molecule of testosterone do not be destroyed immediately the blood they are clung to the various types of esters.

The resulting molecular giants are hydrophobic, hence not soluble in water. All this solution is soluble in fat, but naturally, instead of fat fare used natural oils like peanut, peach and apricot oils. After mixing vegetable oils and essential drug compounds are subjected to special cleaning. This kind of cleaning is required to destroy all microorganisms, settled in the solution and removal of all unnecessary foreign particles and suspensions.

But it happens that not you injected the steroid and get covered with a red rash. What is this? This means that your body along dice oil. Have to be noted that this happens sooner or later to any use of chemistry. The factory such a dirty ampule happens to comes one to an average of one hundred.

It happens that the oil is not warmed to the desired temperature and sealed ampoules. Despite this in many cases, all these spoilage steroids are sold on pharmacy. That way you should not buy cheap chemicals and purchase it from a person you have never seen before in your life.

Best of all is to have a permanent drag dealer and purchased only through him. This tandem is very advantageous for both of them: the dealer has a regular customer, and the buyer has quality and pure chemistry.

Must Read: Is buying injectable steroids online safe?

Let’s see how steroid injection works. Once you have made yourself an injection of an oily preparation, it is deposited in the so-called fat depots. Steroid can be stored there for a long time from a couple of days (like Propionate and Primobolan) up to a year (all known Deca).

Must Read: Guide on Injecting Anabolic Steroids

The degree of resorption and the use of the drug depends on ether. The longer the ester side chain is the longer stays in the fat depot preparation. Such dissolved in the fat depot medication is gradually released into the blood. Of course, the blood brings the molecule hormones to all cells in the body, but even it knows that the concentration in the site of steroid injection is always much higher than in other parts of the body.

This thesis confirms the experience of numerous athletes for injecting steroids in the shoulder biceps and triceps, thigh and hip. I noticed a considerable increase in the affected tissues. However, it should be noted that these injections are not always quite pleasant and are painful.

The advantages of such steroids appear immediately. It is rare to receive one to three vials per week. Let's say you do not need to take 6 tablets of methane daily, but you can just stab a bottle of Deca and happy go the whole week before the next injection, and nothing to worry about.

The curve of the rise and fall of the strength of the drug varies among different steroids. If, for example, the same Propionate begins to act after a couple of hours after the injection, then the results of Deca injection appears will be visible within five days. It is clear that injecting steroids are caught on doping tests elementary.

This is especially true for Deca. It can be reached in urine, even half a year after the last injection. The main advantage of injecting drugs is their low toxicity to the liver and kidneys. Even the strongest and most androgenic drugs in injectable form are less dangerous in relation to their oral counterparts.

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So, Summarizing the Above we Have:

Summarizing

Injectable steroids are comfortable and uncomfortable at the same time to use. It is inconvenient for those who fear needles, but convenient that the injection can be done from once a week or more, and do not eat handfuls of pills daily.
The validity of most of injecting steroids is significantly more than their oral counterparts from three days to a month.
Allocation of the drug in the blood from the fat depots is almost uniformly at certain stages. And it is very convenient as regular hormonal explosions in the body even more harmful than a huge dose of the same oral steroids.
Many injectable drugs are easily reached in case of doping control.
Such drugs are straining your liver in the tens or even hundreds of times less than oral steroids.

So, it is clear that injectable steroids are more advantageous for you. Meantime, need to be aware that there are cases when oral steroids are irreplaceable. That’s why many athletes add to their injectable steroid course some oral steroids too.

But if you are an amateur who needs to gain weight, then inject steroids is your path. Forget about oral steroids, whereas your liver is still more important.

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F Kyle

The "GYMRAT" of this blog, Pro-blogger and Fitness Instructor since 2008

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Steroids

Creatine vs Myostatin: An Expert’s Analysis

Published

7 days ago

March 20, 2025

Sane

Myostatin, a protein encoded by the MSTN gene, acts as a regulator of muscle growth. High levels of myostatin limit the body's ability to build muscle, effectively putting a cap on potential hypertrophy. Inhibiting myostatin has become a focal point for bodybuilders looking to break through plateaus and achieve significant muscle gains. The question is: can creatine, a popular and widely available supplement, help in this regard?

Medical History of Myostatin and Creatine

Myostatin and creatine, while popular now in the bodybuilding world, have their roots in entirely different contexts:

Myostatin: Natural Muscle Growth Regulator

Myostatin is a protein originally identified for its role in regulating skeletal muscle mass. In nature, it serves an evolutionary purpose: by limiting muscle growth, it conserves energy, ensuring that animals (and humans) don’t expend unnecessary resources maintaining excessive muscle tissue. This was especially important in the wild, where energy efficiency could mean the difference between survival and extinction.

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In the medical field, research into myostatin has focused on its role in muscle-wasting diseases. Scientists are exploring ways to inhibit myostatin to treat conditions like muscular dystrophy, where excessive muscle loss impairs quality of life. This therapeutic potential is where the idea of myostatin inhibition first began—long before bodybuilders latched onto the concept.

Creatine: Energy and Medical Applications

Creatine was originally studied for its role in energy metabolism. It’s a naturally occurring compound stored in muscle cells and plays a critical part in replenishing ATP (adenosine triphosphate), the body’s primary energy currency during short, high-intensity activities.

Before becoming a bodybuilding staple, creatine gained recognition in medical and sports science for its ability to improve athletic performance and assist with recovery. Furthermore, in medicine, creatine was investigated for neurological conditions such as Parkinson’s disease, Huntington’s disease, and muscular dystrophy, given its potential to improve muscle function and brain energy metabolism.

In the sports world, it was initially adopted by sprinters and weightlifters in the 1970s and 1980s for its energy-enhancing benefits.

Both myostatin and creatine have found new life in bodybuilding circles, demonstrating how discoveries in natural physiology and medical science can lead to transformative applications in fitness.

Benefits of Creatine as a Myostatin Inhibitor

Muscle Growth Potential: Research suggests that creatine, when paired with intense resistance training, may inhibit myostatin to a degree, fostering an environment for enhanced muscle growth.

Improved Exercise Performance: Creatine is well-known for its ability to increase ATP production, translating to better performance during high-intensity activities.

Versatility Across Fitness Levels

Whether you're a beginner or an advanced athlete, creatine offers benefits that complement various stages of muscle-building.

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Affordability and Accessibility

Compared to specialized myostatin inhibitors like YK-11 and ACE-031, creatine is significantly more affordable and accessible.

Side Effects of Creatine

While generally safe for most individuals, creatine supplementation does come with some potential side effects:

Water Retention: Some users experience bloating due to increased water retention in muscle cells.

Gastrointestinal Issues: High doses may lead to stomach upset or diarrhea.

Kidney Concerns: Although rare, prolonged excessive use could strain the kidneys, particularly in individuals with pre-existing conditions.

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Alternatives to Creatine for Myostatin Inhibition

YK-11: A synthetic myostatin inhibitor derived from SARMs, offering more potent results but accompanied by more significant risks.

ACE-031: A peptide that directly inhibits myostatin, though it remains in experimental phases and is not legally approved in many regions.

Natural Alternatives

Follistatin-rich Foods: Eggs and dairy products may have natural myostatin-inhibiting properties.

Resistance Training: Intense and consistent weightlifting alone can naturally lower myostatin levels.

Where to Buy Creatine

Creatine is readily available worldwide. It can be purchased from:

Local Pharmacies and Nutrition Stores: Ideal for trusted and immediate access.

Online Platforms: Websites like Amazon, iHerb, or bodybuilding-specific stores offer a variety of brands and formulations.

Supplement Brands: Well-established brands such as Optimum Nutrition, MyProtein, and Cellucor often carry high-quality creatine.

Legality of Myostatin Inhibitors

Creatine: Creatine is completely legal and widely accepted as a dietary supplement.

YK-11 and ACE-031: These compounds exist in a legal gray area in many countries due to their experimental nature and potential risks. It's essential to research local laws before considering these options.

Best Stores and Suppliers

For reputable products, consider:

Transparent Labs: Known for purity and transparent labeling.

Optimum Nutrition: Offers pharmaceutical-grade creatine monohydrate.

Bulk Supplements: A great choice for bulk buyers seeking affordability and quality.

Our Advice to Bodybuilders

Always consult with a healthcare professional before starting any new supplement, especially if you are already using AAS or other advanced compounds.

Prioritize a balanced diet and consistent exercise routine. Supplements like creatine work best as part of a holistic approach to fitness.

Stay hydrated while using creatine to minimize water retention side effects and support kidney health.

Related Article: Best Syringes for Steroid Injection on Amazon

Overall

While creatine may not be as potent a myostatin inhibitor as advanced compounds like YK-11 or ACE-031, its affordability, safety, and accessibility make it a valuable addition to any bodybuilder's supplement stack. By leveraging its benefits alongside proper training and nutrition, you can maximize muscle growth and overcome plateaus, regardless of your fitness level.

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Steroids

Raloxifene (Evista) 101: A Non-Surgical Solution for Gyno

Published

2 weeks ago

March 11, 2025

Sane

Raloxifene, a selective estrogen receptor modulator (SERM), is one of the most valuable yet less common options available today. Originally developed to prevent and treat breast cancer similar to Tamoxifen, it has gained popularity among bodybuilders seeking to prevent or eliminate gyno.

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Unlike Tamoxifen, Raloxifene is potent enough to reduce long-standing gynecomastia and is frequently used to reverse pubertal gynecomastia. While it can also boost testosterone levels, it is one of the weaker SERMs in this regard.

How it Works

Raloxifene functions by blocking estrogen receptors in the breasts, which helps prevent or treat both gynecomastia and breast cancer. Additionally, it blocks estrogen receptors in the hypothalamus, stimulating testosterone production.

Beyond these primary benefits, Raloxifene can enhance bone mass, combat osteoporosis, and lower cholesterol levels.

Potential Side Effects

While Raloxifene is considered a generally safe and effective medication, like all drugs, it comes with its own set of potential side effects. One of the most notable is the reduction in Insulin-like Growth Factor 1 (IGF-1) levels. IGF-1 plays a key role in muscle growth and repair, so decreased levels could potentially impact athletic performance or recovery.

However, compared to other medications in its class, Raloxifene has a relatively low risk of causing severe liver toxicity. Users are less likely to experience harmful effects such as blood clots, mood swings, or sexual dysfunction, making it a preferable choice for many.

While rare, some users might experience less serious side effects such as hot flashes, leg cramps, or flu-like symptoms. It's essential to consult with a healthcare professional to monitor any adverse reactions and ensure the medication is being used safely.

So, despite its efficacy, Raloxifene is not without side effects, but they are typically manageable and less severe compared to other SERMs.

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For gyno reversal, the typical protocol involves taking 60mg daily for 1-2 weeks, followed by 30mg daily for up to 3 months or until the condition resolves.

Typical Protocol

For gynecomastia reversal, the typical protocol involves taking 60mg of Raloxifene per day for 1-2 weeks, followed by a reduced dose of 30mg per day for up to 3 months or until the gynecomastia is resolved. In post-cycle therapy (PCT), bodybuilders generally take 60mg per day for 4-6 weeks, and then lower the dose to 30mg per day during the last week. Raloxifene is highly effective for managing gynecomastia and supporting post-cycle recovery, making it a valuable addition to a well-optimized bodybuilding regimen.

Overall

Raloxifene (Evista) is a versatile SERM used to treat breast cancer and is popular among bodybuilders for managing gynecomastia (gyno). Unlike Tamoxifen, it effectively shrinks long-standing gyno and reverses pubertal gyno. It blocks estrogen receptors in the breast and hypothalamus, thus preventing gyno and promoting Testosterone secretion. Additionally, it improves bone mass, combats osteoporosis, and lowers cholesterol levels. For gyno, take 60mg/day for 1-2 weeks, then 30mg/day for up to 3 months. For post-cycle therapy (PCT), take 60mg/day for 4-6 weeks, then reduce to 30mg/day during the final week. This safe and effective medication has minimal side effects.

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Bodybuilding

Mastering Bodybuilding in 2025: Top Fitness Tips for Success

Published

4 weeks ago

March 1, 2025

Sane

Bodybuilding is more than just a sport; it's a lifestyle that requires dedication, discipline, and a thorough understanding of fitness principles. As the world of fitness continues to evolve, bodybuilders must stay updated with the latest trends, techniques, and scientific advancements to achieve their goals. In 2025, several innovative approaches are redefining bodybuilding. Here are essential fitness tips for bodybuilders to excel this year.

Embrace Technology-Driven Workouts

In 2025, technology plays a significant role in bodybuilding. Wearable devices, fitness apps, and virtual reality (VR) training are now integral components of an effective workout regimen.

Wearable Devices

Modern wearables track everything from heart rate and sleep patterns to muscle activation and caloric expenditure. Utilize these devices to monitor your progress and make data-driven adjustments to your training and nutrition plans.

Fitness Apps

Leverage fitness apps for customized workout plans, progress tracking, and virtual coaching. Many apps now incorporate artificial intelligence to provide personalized feedback and recommendations.

Virtual Reality Training

VR technology offers immersive workout experiences, allowing bodybuilders to simulate different training environments and scenarios. This can enhance motivation and add variety to your routine.

Focus on Functional Strength

While hypertrophy (muscle growth) remains a primary goal, functional strength is gaining importance. Functional strength training improves overall performance, reduces the risk of injury, and enhances daily activities.

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Compound Movements

Incorporate compound exercises like squats, deadlifts, and bench presses. These movements engage multiple muscle groups and joints, promoting balanced strength development.

Core Stability

Prioritize exercises that strengthen the core, such as planks, Russian twists, and leg raises. A strong core supports better lifting mechanics and reduces the risk of lower back injuries.

Optimize Nutrition for Muscle Growth and Recovery

Nutrition is the cornerstone of successful bodybuilding. In 2025, the focus is on personalized nutrition plans tailored to individual needs and goals.

Protein Intake

Ensure adequate protein intake to support muscle repair and growth. Aim for 1.6 to 2.2 grams of protein per kilogram of body weight per day, depending on your training intensity and goals.

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Nutrient Timing

Pay attention to nutrient timing to maximize muscle recovery and growth. Consume protein and carbohydrates within 30 minutes post-workout to replenish glycogen stores and kickstart muscle repair.

Supplements

Utilize supplements wisely. Creatine, branched-chain amino acids (BCAAs), and omega-3 fatty acids are popular choices for enhancing performance and recovery.

Prioritize Mental Health and Mindfulness

Mental health is increasingly recognized as a critical component of overall fitness. Incorporating mindfulness practices can improve focus, reduce stress, and enhance performance.

Meditation

Incorporate meditation into your daily routine to reduce stress and improve mental clarity. Mindfulness meditation can enhance your mind-muscle connection during workouts.

Visualization

Use visualization techniques to mentally rehearse your workouts. Visualizing successful lifts and achieving your goals can boost confidence and motivation.

Rest and Recovery

Prioritize rest and recovery to prevent burnout and overtraining. Ensure you get 7-9 hours of sleep per night and incorporate rest days into your training schedule.

Leverage Advanced Training Techniques

Advanced training techniques can help break through plateaus and stimulate muscle growth. In 2025, several methods are gaining popularity among bodybuilders.

Blood Flow Restriction (BFR) Training: BFR involves restricting blood flow to the muscles during low-intensity exercises. This technique can enhance muscle growth and strength without the need for heavy weights.

Eccentric Training: Focus on the eccentric (lowering) phase of exercises. Eccentric training can stimulate greater muscle damage and growth compared to traditional concentric movements.

Periodization: Implement periodization into your training plan. Varying the intensity, volume, and type of exercises can prevent plateaus and ensure continuous progress.

Incorporate Recovery and Mobility Work

Recovery and mobility are essential for preventing injuries and maintaining optimal performance. In 2025, bodybuilders are paying more attention to these aspects of training.

Foam Rolling and Myofascial Release: Use foam rollers and massage balls to release muscle tightness and improve flexibility. Regular myofascial release can reduce soreness and enhance recovery.

Stretching: Incorporate dynamic stretching before workouts and static stretching after workouts. Stretching improves range of motion and prevents muscle imbalances.

Cryotherapy and Hydrotherapy: Explore recovery techniques like cryotherapy (cold therapy) and hydrotherapy (water therapy) to reduce inflammation and accelerate muscle recovery.

Engage in Continuous Learning and Community Building

The fitness industry is constantly evolving, and staying informed is crucial for success. Engage in continuous learning and connect with the bodybuilding community for support and motivation.

Educational Resources: Read books, watch videos, and attend seminars to stay updated on the latest research and trends in bodybuilding.

Community Engagement: Join online forums, social media groups, and local bodybuilding clubs. Sharing experiences and knowledge with fellow bodybuilders can provide valuable insights and encouragement.

Professional Guidance: Consider working with a certified personal trainer or coach. Professional guidance can help you optimize your training and nutrition plans, ensuring you're on the right track.

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Conclusion

In 2025, bodybuilding is more than just lifting weights; it's a holistic approach to fitness that encompasses technology, nutrition, mental health, and advanced training techniques. By embracing these fitness tips, bodybuilders can achieve their goals, stay injury-free, and enjoy a fulfilling fitness journey. Remember, consistency and dedication are key to success in bodybuilding. Stay committed, keep learning, and most importantly, have fun on your path to becoming the best version of yourself.