Steroids

Why Prohormones Are Not Better Than Steroids

Published

11 years ago

December 11, 2013

Zizou

The media make us believe that steroids are harmful to our health. If you have some experience with steroid use, you know how things are, but a novice can take it as truth. What do they do? They begin to look for safer alternatives to steroids, which are considered to be prohormones. Right from the start, I want to say that prohormones are not even far safer than anabolic steroids. But before enumerating the reasons, let’s pay attention to one crucial detail.

Steroids are illegal. Twenty-three years ago, they were included in the list of controlled drugs, and their use is prohibited. You can get into jail for using steroids. Prohormones are legal. You can buy in stores with no fear of being punished. Prohormones tend to be claimed as being natural hormones, hence being safer than steroids. They need to convert into steroids once entering the body, while anabolics act as hormones instantly.

Must Read: The Proper Approach to Buying Steroids Online (updated)

You must know that prohormones are synthetic compounds and can not be found in nature. Just as the anabolic androgenic steroids are. It means that prohormones are the same steroids but “dressed” in legal form. They are not safer, more efficient, or more natural than anabolic steroids are.

The simple fact that prohormones are categorized as legal drugs is not an indication that they will not cause you health problems. Contrary to this, you may experience during their use of severe side effects, while the gains you make will be far from the expected ones.

Prohormones have more Accentuated Side-Effects:

Side Effects

You expect less or no damage to your health since you were told prohormones are “natural.” You are wrong if this was your main reason for choosing these drugs. Prohormones are far worse than steroids in side effects profile. The most common side effects that you can expect while running prohormone cycle are:

-Acne. A solution is to apply acne creams on affected areas, but the signs left over your body will look very unaesthetic.

-Hair loss. Over the last years have been created more inoffensive forms of prohormones to minimize this effect, but it is still widespread.

-Gynecomastia. It is the number one side effect most prohormones users complain about products. Just take a look on steroids boards and convince yourself that most people complain about developing gyno with minimum consumption of prohormones.

-Testicular shrinkage.

Prohormones are Liver Toxic:

Prohormones are Liver Toxic

Far more than oral steroids. Prohormones are 17-alkylated, which means they were changed to a degree to bypass the liver and get to muscles that trigger anabolic activity. This level is high and presents a significant risk for your liver health.

Must Read: Liver Damage While On Oral Steroids

Prohormones must be taken in a higher dosage than oral steroids to reach the same results. Simply put, it means the more you take, the more you expose your liver and may irremediably damage it.

Prohormones Provide Modest Results:

Prohormones Provide Modest Results

These chemicals are less effective than anabolic, despite the side effects they carry being more pronounced. Prohormones will never help you build the strength, power, muscle mass, or endurance anabolic steroids can do. You take too many risks for lower results than you get with anabolics. Does it worth it? I’m sure you have the same answer: no.

Injectable steroids are by far more efficient and less dangerous. Prohormones cannot be found in injectable form, so you have to limit them to oral ones, which are the last that you are advised to choose from the wide range of body performance-enhancing drugs.

Prohormones are Not Studied Enough:

Prohormones are not Studied Enough

Neither steroids nor prohormones are studied enough to come up with scientific opinions about their usage and side effects in the long term. For the most part, our knowledge about these hormonal drugs is based on the experience of steroid users.

However, to be correct enough, AAS was a bit more analyzed, and in turn, they were included in the list of banned drugs. Prohormones are marketed as “natural” hormones, but very little scientific research supports this claim.

Prohormones Cycles have to Be Followed By a PCT Period:

Like in the case of the steroid cycle, you need to take antiestrogens to keep your estrogen level within normal limits and some Nolvadex or Arimidex to help your body restore its testosterone production once the cycles are over. Missing this part of the cycle is going to push you into serious health problems.

So, if you planned to run a prohormone cycle to save money on PCT drugs, then you are wrong, you have to allow the same budget as in the case of steroids cycles, but the results will not be so stunning.

MUST-READ: 5 Best Steroid Cycles for Beginners

Which Individuals Should Not Use Prohormones at all?

Prohormones as anabolic steroids fit people older than 21 years with several years of training. It means that these people know their bodies, what diet to follow to grow, how hard they need to train to gain muscle mass, and what supplementation works great for them. Prohormones are strictly prohibited for use for people with heart, liver, kidney, or other serious diseases. Their use can worsen any of these conditions.

Whatever your reason for using prohormones, know that these drugs are not safer, more natural, or more effective than anabolic steroids. Instead, they carry a high toxicity level than oral AAS. It is just about fewer gains with higher risks. No prohormone drug could be more efficient than any steroid, and even a complete prohormone cycle cannot provide the results anabolics put on you.

A final thought to consider: if prohormones were so efficient and safe, why do they continue to be less prevalent despite their legacy? On the other side, anabolic steroids are illegal, but there is a much higher demand for them yearly. Let us know your opinion about this in the comments below.

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Steroids

Reviews

Published

16 hours ago

May 16, 2025

Sane

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Steroids

ACE-031: A Powerful Myostatin Inhibitor

Published

2 days ago

May 15, 2025

Sane

ACE-031 is a synthetic peptide designed to block myostatin, a natural regulator of muscle growth. Developed by Acceleron Pharma, it was originally studied as a treatment for muscle-wasting conditions like muscular dystrophy. By inhibiting myostatin, ACE-031 enables unrestricted muscle growth, making it appealing to athletes and bodybuilders seeking increased muscle mass and strength.

Benefits for Bodybuilders

ACE-031 offers significant advantages for bodybuilders aiming to maximize muscle growth:

Enhanced Muscle Development – By blocking myostatin, ACE-031 eliminates the biological limit on muscle expansion, allowing for significant increases in lean muscle mass.

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Improved Endurance and Fat Reduction – Users may experience enhanced endurance and reduced fat accumulation, which contributes to overall body composition improvements.

Accelerated Recovery – The peptide aids in muscle repair, shortening recovery time after strenuous workouts and enabling more frequent training sessions.

These benefits make ACE-031 a valuable tool for bodybuilders seeking superior performance and rapid results.

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Potential Side Effects

While ACE-031 delivers powerful muscle-building effects, it is not without risks:

Swelling in Limbs – Some users report fluid retention and swelling, particularly in the arms and legs.

Weakened Tendons and Ligaments – Rapid muscle growth may surpass the body's ability to strengthen tendons and connective tissues, potentially leading to strain or injury.

Unknown Long-Term Effects – Since human studies on ACE-031 are limited, the full scope of potential risks remains uncertain.

Given these concerns, careful monitoring and responsible use are essential.

Recommended Dosage and Cycling

Due to its potency, ACE-031 should be dosed conservatively:

Beginner Dosage – 1 mg per week, injected subcutaneously or intramuscularly, to assess tolerance.

Experienced Users – Up to 3 mg per week, but only with caution and close observation for adverse effects.

Cycling Approach – A typical cycle lasts 4–6 weeks, followed by a break to prevent desensitization and allow the body to reset.

Using ACE-031 responsibly within structured cycles helps mitigate risks and optimize benefits.

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Potential Alternatives to ACE-031

Here are 10 alternatives to ACE-031 that also function as myostatin inhibitors or support muscle growth through similar mechanisms:

Follistatin-344 – A potent myostatin inhibitor that promotes muscle hypertrophy by blocking myostatin activity.

BPC-157 – Known for its regenerative properties, it enhances healing and tissue repair, indirectly supporting muscle growth.

CJC-1295 – A growth hormone-releasing peptide that boosts GH levels, aiding in muscle development.

Ipamorelin – Stimulates GH release with minimal side effects, making it a safer option for muscle enhancement.

MK-677 (Ibutamoren) – A powerful GH secretagogue that promotes muscle growth and fat loss.

Sermorelin – Encourages natural GH production, supporting recovery and lean muscle gains.

Tesamorelin – Primarily used for fat loss but also aids in muscle preservation.

PEG-MGF (Pegylated Mechano Growth Factor) – Enhances muscle repair and growth post-exercise.

GHRP-6 – Stimulates appetite and GH release, supporting muscle mass gains.

Activin A Blockers – Experimental compounds that target the myostatin pathway to enhance muscle growth.

Each of these alternatives has unique mechanisms and benefits, so selecting the right one depends on your specific goals.

ACE-031 is available in several forms for purchase, depending on the supplier. Here are the common options:

Peptide Vial – Typically comes in 1 mg vials for reconstitution.

Pre-Mixed Pen – A ready-to-use injectable form for convenience.

Nasal Spray – An alternative delivery method for those avoiding injections.

Peptide Stacks – Some suppliers offer ACE-031 combined with IGF-1 LR3 for enhanced muscle growth.

You can find these forms from suppliers like PharmaLabGlobal and Direct Peptides.

Related Article: Anavar Cycle for Men and Women

Overall

ACE-031 presents promising muscle-building advantages, making it a sought-after peptide among bodybuilders. However, due to limited research and potential side effects, users should approach it with caution, adhere to recommended dosages, and seek professional guidance to ensure safe usage.

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Steroids

Decoding IGF-1 LR3: A Guide to its Benefits

Published

3 weeks ago

April 25, 2025

Sane

IGF-1 LR3 (Insulin-like Growth Factor-1 Long Arg3) is a synthetic variant of IGF-1, a hormone produced by the liver in response to growth hormone (GH). Unlike GH, which works indirectly, IGF-1 directly facilitates the growth and repair of muscle cells.

Related Article: Ostarine for Beginners; The Ultimate Guide

This modified version of IGF-1 is engineered to avoid binding with IGF-binding proteins, extending its half-life to 20–30 hours. As a result, it remains active in the body significantly longer than natural IGF-1.

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Many performance athletes incorporate IGF-1 LR3 post-workout to enhance muscle growth, speed up recovery, and support fat loss. When injected into specific muscle groups, it often produces localized effects. Additionally, it helps with nutrient distribution and, in some cases, improves insulin sensitivity.

On the other hand, human growth hormone (HGH) operates more broadly and indirectly, stimulating the liver to produce IGF-1 and offering more systemic benefits such as improved skin health, joint support, and fat reduction, albeit at a slower pace.

Typical IGF-1 LR3 doses range from 20–50 mcg daily, administered subcutaneously or intramuscularly, often following a workout.

Key Features of IGF-1 LR3

Enhanced Bioavailability: It avoids binding with IGF-binding proteins, increasing its potency.

Muscle Growth & Repair: Directly stimulates muscle cell proliferation and differentiation.

Improved Nutrient Distribution: Helps shuttle nutrients into muscle cells, supporting recovery.

Potential Fat Loss Benefits: Some users report improved insulin sensitivity and fat metabolism.

Mechanism of Action

IGF-1 LR3 interacts with IGF-1 receptors on muscle cells, activating pathways like PI3K-AKT and MAPK, which are crucial for cell growth and regeneration. This makes it a powerful tool for bodybuilders and athletes looking to optimize recovery and muscle development.

What Are the Top 10 Alternatives to IGF-1 LR3?

Here are some of the top alternatives to IGF-1 LR3, each with unique benefits for muscle growth, recovery, and performance:

BPC-157 – Known for its regenerative properties, it enhances healing and tissue repair.

CJC-1295 – A growth hormone-releasing peptide that boosts GH levels for muscle development.

Ipamorelin – Stimulates GH release with minimal side effects, making it a safer option.

MK-677 (Ibutamoren) – A potent GH secretagogue that promotes muscle growth and fat loss.

Sermorelin – Encourages natural GH production, supporting recovery and lean muscle gains.

Tesamorelin – Primarily used for fat loss, but also aids in muscle preservation.

Follistatin-344 – Inhibits myostatin, allowing for increased muscle hypertrophy.

PEG-MGF (Pegylated Mechano Growth Factor) – Enhances muscle repair and growth post-exercise.

GHRP-6 – Stimulates appetite and GH release, supporting muscle mass gains.

GHRP-2 – Similar to GHRP-6 but with fewer hunger-related side effects.

Each of these peptides has distinct mechanisms and benefits.

Must Read: Are Nootropics a Better Option to AAS?

Potential Risks Associated With IGF-1 LR3

IGF-1 LR3 comes with several potential risks, especially for bodybuilders using it to enhance muscle growth. Here are some key concerns:

Hypoglycemia (Low Blood Sugar) – IGF-1 LR3 increases glucose uptake in muscle cells, which can lead to dangerously low blood sugar levels if not managed properly.

Organ Growth – Since IGF-1 affects all tissues, excessive use may lead to unwanted growth in organs, increasing health risks.

Cancer Risk – IGF-1 plays a role in cell proliferation, and elevated levels have been linked to an increased risk of certain cancers.

Water Retention & Edema – Some users experience bloating and fluid retention, which can affect performance and aesthetics.

Joint Pain & Stiffness – Excessive IGF-1 levels may contribute to joint discomfort due to increased tissue growth.

Cardiovascular Issues – There is some concern that IGF-1 LR3 could contribute to heart enlargement or other cardiovascular complications.

Desensitization – Long-term use may reduce the body's natural IGF-1 production, leading to dependency

Overall

IGF-1 LR3's ability to bypass IGF-binding proteins makes it more potent but also increases the likelihood of desensitization with prolonged use. For those considering it, careful dosing and monitoring are crucial to mitigate side effects.