Steroids
SARMs For PCT (Post Cycle Therapy)?
There has been a lot of speculation going around in the past. Is it reasonable to use Selective Androgen Receptor Modulators (SARMS) in your Post Cycle Therapy (PCT)? However, anabolic steroid is much more popular than SERMs among bodybuilders. Is it that they are believed to be more effective? The number of people using PCT is much lesser than those who opt to use SARMs on their Post Cycle Therapies.
The main reason is that using Selective Androgen Receptor Modulators is not advisable. If you use SARMs for your PCT, then it is the high you reconsidered.
SARMs At A Glance
Selective Androgen Receptor Modulators (SARMs) are a class of androgen receptor ligands that are tissue selective or specific to certain tissues. They have the potential to treat muscle wasting and osteoporosis, as well as male breast cancer.
The term SARMs was coined in 2003 by scientists at Ligand Pharmaceuticals. This new drug class aims to avoid the side effects caused by testosterone while maintaining its anabolic effects. Selective Androgen Receptor Modulators are a new class of drugs recently developed to avoid the side effects caused by testosterone while retaining its anabolic effects.
The most commonly studied androgen receptor agonist is known as ostarine. Ostarine is a selective androgen receptor modulator that binds to the AR in a tissue-specific manner, thus acting similarly to endogenous hormones such as testosterone without significant unwanted effects on the female reproductive system.
It is effective as a muscle-building agent but has also been found to have anabolic effects on bone, fat, and muscle mass. Because of these benefits, ostarine is often prescribed for osteoporosis, obesity, and muscle wasting.
The first SARMs (1-ethyl-7-(3-methyl butyl) pyrazolo [3,4-d]-pyrimidine) was developed by Ligand Pharmaceuticals in 2003. Ostarine was the first SARM to be marketed, with its main effects being increased skeletal muscle mass and strength and reduced fat mass.
Other SARMs have also been developed and are used in the bodybuilding and sports performance fields.SARMs have been tested by some of the world's most prestigious athletic organizations, including the United States Anti-Doping Agency, the US Biathlon Association, and the International Olympic Committee.
A study on Ostarine conducted by USADA found an average serum concentration of less than 0.1ng/mL when taken under recommended conditions.
Why SARMs for PCT?
Various science sectors have conducted research as to what the effect of SARMs and PCTs is on the body. Do they both help in a mass gain? Which one is more effective? Do you need to use PCT while using SARMs? Some of the anabolic steroids used by many include the likes of Masteron, Oxandrolone, and Primobolan.
Using such steroids, one gets much more suppression than when one uses SARMs. However, no conclusive research has been established to support this statement. This will not be the first place such a conclusion has been made.
Must Read: What are SARMs (Selective Androgen Receptor Modulators)?
Most scientific research conducted by well-known firms tends to beat around the bush. The most famous statement from these researches is that 'no element (x) has significantly been traced.' In other cases, it is said that the change I (x) was not significant.
Inconclusive Research:
Contrary to what the majority think, such statements do not mean what they seem to suggest. There is a whole other meaning attached to them. They imply no effect was found on the exact amount used for the tests. Usually, a small number of subjects are used for such studies.
In addition to this, the variations experienced are usually random. Therefore, nothing conclusive can be established. However, a certain amount of threshold is generally experienced. To state that 'no effect' was visible is incorrect.
This explains why many scientific researchers claim that anabolic steroids do not affect mass gain as a worn cement of performance. The keyword here is "no." The accurate conclusion should be that there was some change though it has no statistical significance.
Is SARMs Non-Inhibitory?
Well, the answer to this question is not conclusive at the moment. But the various types of research are nothing to go by. As shown above, how the conclusions are worded is somehow questionable. Whether or not they are non-inhibitory, they are equivalent to taking anabolic steroids during PCT.
Their effect is the same, but the doses will separate them. If carefully used, SARMs tend to affect the PCT positively. However, if arrogantly used, they tend to set back one's recovery.
Are SARMs Legal?
The World Anti-Doping Agency (WADA) has not banned SARMs because they are not on their prohibited substances list, but they are concerned that some athletes could be using them to gain an unfair advantage.
The FDA is also investigating whether or not SARMs should be considered dietary supplements and controlled since no research shows a risk of long-term health problems. The peptide is a small protein that is the building block of many hormones in the body. People often test for specific peptides to get an idea of the body's natural hormone levels.
The most common tests for levels of these peptides include:-Cortisol - Cortisone-Urinary Free Testosterone - UFPT-Thyroid Stimulating Hormone - TSHAlmost every drug type available on the market is either regulated by the FDA or else classified as a dietary supplement.
There are a few exceptions, such as benzodiazepines and stimulant drugs, which must be controlled by prescription.SARMs do not have any research behind them, and we don't know their long-term effects.
The peptide also has not been approved or regulated as a drug, so it falls under the category of 'drug'. Studies show that there is a possibility for a drug to be created from epinucleotide. Preparation of the drug is relatively easy as it is a peptide. The peptide can quickly be bonded to any method and affects the brain in different ways, seen with other drugs.
Possible side effects of the drug have not been studied yet, but studies show that it could have adverse effects such as addiction or brain damage. In addition, studies show an increase in the risk of developing a substance use disorder with long-term use.
Must Read: Advice on Prohormone Stack Cycle, SARMS, Albuterol
Conclusion:
Users of SARMs for their PCT have explained that it tends to go a long way in helping with joint pains. However, this is not always the case. Yes, with SARMs, you will not necessarily need PCT. But, irregular use tends to have some adverse effects on the body.
There have been cases of eyesight turning yellow permanently for some. In other cases, the recovery period is extended, making the whole process unbearable. At the end of the day, why not be safe rather than sorry? Anabolic steroids are the safest bet, although they, too, have their flipside!
Bodybuilding Products
Counteracting Anabolic Resistance with Adaptogens in Aging Men
As people age, maintaining muscle mass and strength becomes increasingly challenging due to a natural condition called anabolic resistance. This phenomenon, where muscles become less responsive to exercise and protein intake, can start as early as age 40. However, adaptogens—herbs that help the body adapt to stress—are emerging as promising allies in combating this resistance and promoting muscle health.
Understanding Anabolic Resistance Symptoms
Aging athletes may experience several symptoms of anabolic resistance, including:
Decreased Muscle Protein Synthesis
Muscles become less responsive to protein, affecting growth and recovery.
Increased Cortisol Levels
Chronic stress raises cortisol levels, which can lead to muscle breakdown.
Hormonal Decline
Natural decreases in testosterone and growth hormone reduce muscle-building capacity.
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Top Adaptogens for Muscle Health
Some of the most commonly used adaptogens include Ashwagandha, Rhodiola Rosea, and Panax Ginseng. Their key benefits are:
Ashwagandha
-
- Supports testosterone levels.
- Reduces cortisol, improving recovery and muscle maintenance.
- Enhances endurance for sustained workouts.
Rhodiola Rosea
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- Lowers fatigue and increases stamina.
- Reduces stress, supporting muscle retention.
Panax Ginseng
-
- Boosts energy levels for longer, more effective workouts.
- Supports immune function, aiding in recovery.
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How Adaptogens Support Muscle Tissue and Overall Health
Adaptogens help counteract anabolic resistance by:
Regulating Hormones
Ashwagandha may optimize testosterone and growth hormone levels, essential for muscle maintenance.
Lowering Cortisol Levels
High cortisol can exacerbate anabolic resistance. Adaptogens like Rhodiola and Ashwagandha help reduce cortisol, fostering a more anabolic environment.
Enhancing Energy and Endurance
Rhodiola and Ginseng boost energy levels, helping athletes maintain workout intensity, crucial for combating anabolic resistance.
Boosting Recovery and Reducing Fatigue
Ashwagandha aids muscle recovery, and Rhodiola reduces fatigue, both vital for consistent training intensity.
Tips for Integrating Adaptogens into Your Routine
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To incorporate adaptogens into your daily life, consider these tips:
Start Small
Begin with a lower dose to gauge your body's response.
Cycle Use
Use adaptogens for 6-8 weeks, then take a short break to reset and maintain their effectiveness.
Choose Quality Supplements
Opt for third-party tested and certified supplements to ensure potency and purity.
More Options to Counteract Anabolic Resistance in Older Men
Related Article: Peptides Vs Steroids - A Complete Guide
When it comes to counteracting anabolic resistance in older men, it's important to consider both safety and efficacy. Here are some options that might be beneficial:
Selective Androgen Receptor Modulators (SARMs): These compounds are designed to mimic the effects of anabolic steroids without the severe side effects. They can help increase muscle mass and strength.
Testosterone Boosters: Supplements like Adaptophen contain natural ingredients such as Tongkat Ali, Siberian Rhodiola Rosea, and Elk Antler Velvet, which are promoted to boost testosterone levels, improve muscle growth, and aid recovery.
Human Growth Hormone (HGH): HGH supplements can help increase muscle mass and strength, but they should be used under medical supervision due to potential side effects.
Ecdysterone: This compound is found in certain plants and has been shown to have anabolic effects similar to anabolic steroids but with fewer side effects.
Turkesterone: Another natural compound that has shown promise in increasing muscle mass and strength without the harsh side effects of anabolic steroids.
It's crucial to consult with a healthcare professional before starting any new supplement regimen, especially if you have underlying health conditions or are taking other medications. They can help you determine the best course of action based on your individual needs and health status.
Recommended Exercises to Restore Muscle In Older Men
Restoring muscle loss in older men can be effectively achieved through a combination of resistance training and functional exercises. Here are some of the most effective exercises:
Dumbbell Squats: These help build lower body strength and muscle mass. Stand with feet shoulder-width apart, holding dumbbells at your sides, and squat down while keeping your chest up.
Incline Dumbbell Bench Press: This exercise targets the upper chest and shoulders. Lie on an incline bench, holding dumbbells, and press them upwards until your arms are fully extended.
Chest-Supported Dumbbell Rows: Great for strengthening the back muscles. Adjust the bench to an incline, chest-supported, and pull the dumbbells towards your torso while keeping your back straight.
Planks: Excellent for core strength and stability. Hold a forearm plank position, keeping your body in a straight line from head to heels.
Bird Dogs: This exercise improves core strength and balance. Start in a tabletop position, extend one arm and the opposite leg, and hold for a few seconds before switching sides.
Bodyweight Exercises: Exercises like push-ups, lunges, and step-ups are also beneficial for maintaining muscle mass and overall strength.
Incorporating these exercises into a regular workout routine can help combat muscle loss and improve overall fitness. Remember to start slowly and gradually increase the intensity to avoid injury.
Conclusion
While adaptogens are not a substitute for a balanced diet or structured training, they offer a natural way for aging athletes to manage anabolic resistance. By supporting hormonal balance, reducing stress, enhancing energy, and aiding in recovery and fatigue, adaptogens like Ashwagandha, Rhodiola Rosea, and Panax Ginseng can help athletes, especially those over 40, stay strong and healthy as they age.
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Steroids
Tips on How to Store Peptides and HGH
When peptides are mixed with bacteriostatic water (BAC water), their longevity is highly influenced by how they are stored. Correct storage is crucial, as improper conditions can compromise their quality and reduce their efficacy.
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Key Storage Guidelines
Room Temperature: Peptides tend to degrade rapidly at room temperature, lasting only a few hours to a day. It's best to use them immediately in this condition.
Refrigeration (2-8°C): When stored in a refrigerator, peptides mixed with BAC water can remain stable for 2-4 weeks. However, some peptides may degrade more quickly than others, so limiting storage to around two weeks is safest.
Freezing (-20°C or lower): For prolonged storage, freezing is the best option, maintaining peptide stability for several months. It is important to avoid multiple cycles of thawing and refreezing, as this can degrade the peptides.
It's important to note that storage guidelines can differ depending on the specific peptide, so always check for the particular recommendations to ensure maximum longevity and effectiveness.
NOTE: Peptides reconstituted with Sterile Water only remain potent for 2-3 days, even under ideal storage conditions. This is because sterile water lacks the antibacterial properties of BAC water, leading to faster bacterial growth and peptide degradation.
Finding Containers to Store Peptides and HGH
You can find containers for storing peptides and HGH at various online retailers and specialty stores. Here are a few options:
Edge Peptides: They offer a range of storage containers suitable for peptides, including glass and high-quality plastic vials.
Peptide Sciences: This site provides information on peptide storage and offers appropriate containers.
Muscle and Brawn: They have guidelines on peptide storage and sell containers designed for this purpose.
Make sure to choose containers that are chemically inert, such as glass or high-quality plastic, to avoid any reactions with the peptides. Additionally, ensure the containers are tightly sealed to prevent contamination and degradation.
What Would Be the Best Peptides and HGH for Beginners?
For beginner bodybuilders and athletes, it's important to start with safe and effective options. Here are some of the best peptides and human growth hormone (HGH) supplements:
Peptides for Muscle Growth
Ipamorelin: Stimulates growth hormone production, aiding muscle growth and fat loss.
CJC-1295: Enhances growth hormone release, promoting muscle growth and improving sleep quality.
Hexarelin: Stimulates growth hormone release, aiding muscle gain and cardiovascular health.
Sermorelin: Increases growth hormone production, beneficial for muscle growth.
GHRP-6: Stimulates growth hormone release, increasing energy levels and aiding muscle growth.
HGH Supplements
CrazyBulk HGH-X2: Boosts HGH production, increases energy levels, and helps build muscle mass.
HyperGH 14x: Promotes muscle growth and improves performance.
GenF20 Plus: Maintains optimal HGH levels, aiding in muscle growth and anti-aging.
PGH-1000: Enhances strength and stamina.
Sytropin: Supports physical fitness, anti-aging, and andropause.
Summary
Storing peptides and human growth hormone (HGH) properly is crucial for maintaining their effectiveness and ensuring safety. Peptides should ideally be stored in a refrigerator at 2-8°C for up to 2-4 weeks when mixed with bacteriostatic water, while freezing them at -20°C or lower extends their stability for several months, but avoid thawing and refreezing. When reconstituting peptides, use bacteriostatic water instead of sterile water to maintain potency for a longer duration (2-4 weeks versus 2-3 days). Use chemically inert containers, like glass or high-quality plastic vials, and ensure they are tightly sealed. Maintain sterility during reconstitution and storage to prevent bacterial contamination.
Use reconstituted peptides as soon as possible to avoid degradation in solution. Popular peptides for muscle growth include Ipamorelin, CJC-1295, Hexarelin, Sermorelin, and GHRP-6, while CrazyBulk HGH-X2 is a common supplement to boost HGH production. Always check the specific storage recommendations for each peptide, as they can vary.
Remember, it's crucial to consult with a healthcare professional before starting any new supplement regimen to ensure it's safe and appropriate for your individual needs.
Steroids
Ostarine For Beginners: The Ultimate Guide
Ostarine, also referred to as MK-2866 or Enobosarm, is among the most extensively used and researched Selective Androgen Receptor Modulators (SARMs). Initially developed to combat muscle-wasting diseases, it has gained immense popularity among athletes and bodybuilders for its muscle-preserving and performance-enhancing benefits.
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How Does It Work?
Ostarine selectively binds to androgen receptors in muscle and bone tissues, promoting protein synthesis and osteogenesis. Unlike anabolic androgenic steroids (AAS), which interact with androgen receptors throughout the body, Ostarine specifically targets certain tissues, reducing the risk of unwanted side effects such as hair loss, high estrogen levels, prostate enlargement, or virilization in women.
Practical Benefits of Ostarine
Muscle Preservation
Ostarine is well-known for its ability to maintain lean muscle mass, especially during calorie deficits. Studies have shown that it prevents muscle wasting while sustaining strength and endurance, making it ideal for cutting cycles (Dalton et al., 2011).
Muscle Growth
Although its muscle-building capacity is milder compared to stronger SARMs or AAS, Ostarine effectively promotes gradual, high-quality muscle gains without excessive water retention.
Improved Recovery
Athletes have reported enhanced recovery times with Ostarine. By reducing muscle breakdown and increasing nitrogen retention, it allows users to train more frequently and intensively.
Bone Health
Ostarine positively impacts bone density. Research indicates its ability to increase bone mineralization, potentially making it a therapeutic agent for osteoporosis (Narayanan et al., 2008). For athletes, this translates to a reduced injury risk and stronger skeletal support during heavy training.
Related Article: Legality of Steroids in Latin America
Potential Side Effects
Mild Testosterone Suppression
Ostarine can suppress natural testosterone production, particularly at higher doses. Post Cycle Therapy (PCT) is recommended after cycles to restore hormonal balance.
Dyslipidemia
Like most SARMs, Ostarine can affect lipid profiles, potentially lowering HDL (good cholesterol) and increasing LDL (bad cholesterol).
Elevated Liver Enzymes
Some users report mild elevations in liver enzymes during use, though these usually return to normal after discontinuation.
Long-Term Effects
Unknown As a relatively new compound, the long-term effects of Ostarine on health are not fully understood.
How to Use Ostarine Correctly
Dosage and Cycle Recommendations
Ostarine is typically dosed at 10–30 mg per day, depending on the user’s goals and experience level:
For Cutting: 10–20 mg per day to preserve muscle and aid fat loss.
For Bulking: 20–30 mg per day to promote lean muscle gains.
Cycles generally last 6–8 weeks. Longer cycles or higher doses may increase the risk of side effects, including testosterone suppression. With a half-life of approximately 24 hours, Ostarine allows for convenient once-daily dosing.
Post Cycle Therapy (PCT)
We highly recommend PCT following Ostarine cycles, especially for doses exceeding 20 mg per day, to restore natural testosterone levels.
Ostarine Alternatives
For beginner bodybuilders looking for alternatives to Ostarine, here are some popular options:
- RAD 140 (Testolone): Known for its excellent muscle-building and fat-burning properties, RAD 140 is a favorite among those looking to gain lean muscle mass.
- LGD-4033 (Ligandrol): This SARM is highly effective for increasing strength and muscle mass, making it a great choice for beginners.
- Cardarine (GW-501516): Although not technically a SARM, Cardarine is popular for its ability to enhance endurance and fat loss.
- YK-11: This SARM is known for its ability to promote muscle growth and strength, similar to anabolic steroids.
- S23: Effective for cutting cycles, S23 helps reduce body fat while preserving muscle mass.
- Andarine (S4): This SARM is used for both bulking and cutting, offering muscle preservation and fat loss.
These alternatives offer various benefits and can be chosen based on individual goals and preferences. It's always important to research and consult with a healthcare professional before starting any new supplement regimen.
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Overall
Ostarine (MK-2866) is a versatile and beginner-friendly SARM, offering significant benefits for muscle preservation, recovery, and lean growth. Its selective action and mild side-effect profile make it an attractive option for athletes and bodybuilders seeking an edge in performance and aesthetics. However, responsible use, including appropriate dosing, cycle length, and post-cycle therapy, is crucial to minimizing risks and maximizing results.
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