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Steroids vs Peptides – PROs and CONs

Published

6 years ago

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          Steroids are synthetic drugs just like the natural hormones in the body.  AAS (Anabolic Androgenic Steroids) is the type of steroids, which copy the effect of male hormones and testosterone; used by people to build muscles and to increase strength. AAS are different from corticosteroids, which are medically used to treat asthma. There are more than one meaning of steroid. There is a medicine that's name is “steroid,” which people take to reel asthma and skin problems. Steroids help to reduce stress and increase the growth of the body.

         Do you know there are some illegal anabolic steroids? Yes, the artificially produced hormones like androgens (Male-type sex hormones in the body). Anabolic Steroids are in the form of pills, injections, or powders.

         Athletes use Anabolic Steroids to increase their muscle strength and mass. Girls also use steroids to become stronger. 

       Supplements are also available which contain anabolic steroids. Promoted by the ads and through magazines. Legal and illegal supplements cause health problems. Some are banned in the United States, but some are legal until now. Children’s should not take steroid supplements, either they are present in the market because they are dangerous for health.

Functions of Steroids:

       There are two varieties of steroids developed for medical treatments. One is Anabolic Steroids which you hear most and as we also discussed them. They behave like male sex hormones, and medically they are used for the treatment of problems like late puberty and muscles loss in patients who have cancer and AIDS.

      Although they are used for building muscles yet, they used for the cure of allergic reactions and autoimmune diseases. For autoimmune diseases, especially Prednisone is suggested for treating lupus and arthritis. (it is a famous type of Corticosteroid).

       Anabolic Steroids and Corticosteroids both can be injected muscularly, and they can be either taken orally or by scrubbing on the body. They use in the muscle’s growth. According to research, various kinds of anabolic steroids have been introduced.

Our muscles become hard due to work out because of the creation of micro-tears in muscles fibers. Muscles will restart growing, and with the repetition of this process, they ultimately become hard and colossal. In this regard, the anabolic steroid works best as they enhance the pace of muscle healing by preventing the breakdown of muscle tissues. It is preferable for the use of athletes.

Types of Steroids:

Commonly known as anabolic steroids:

Oral Steroids:

  • Dianabol
  • Oxandrin
  • Anadrol
  • Anavar

Injectable Steroids:

  • Deca-Durabolin ("Deca" for short)
  • Equipoise ("Eq" for short)
  • Testosterone
  • Durabolin
  • Dianabol ("Dbol" for short)
  • Trenbolone

Let’s discuss a few major types:

       Dianabol (DBol) is hormone/organic compound used to increase the ability and working power of the human body. It is widely used for bodybuilding and said the basic of the bodybuilding’s Arnold Schwarzenegger time. Dbol took orally, and it is very poisonous/toxic for liver.

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   Trenbolone Acetate is considered as the best hormone that a person can take either in the beginning or at any time. It is super diverse. Tren made as a veterinary supplement used to increase the size of animals. 

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        Anavar, an oral organic compound used by men and women. A modest steroid and di-hydro testosterone obtained, frequently prescribed by doctors for gaining weight. Anavar is a constructive metabolism rating 3–6x higher than average testosterone. Anavar used as an “initial” steroid because of fewer side effects and want of strong androgenic effects.

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       Deca Durabolin is a derivative of Nandrolone. It is less harmful than testosterone. The reason for Deca popularity is bulking steroid and its minimal side effects.

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PROs of Steroids:

     Steroids said as performance-enhancing drugs used to enhance natural body performance. Artificial steroids used for the growth of reproductive organs, bones, body, hair, and muscles, proved by research.

  •    Stamina Testosterone steroids used to improve the stamina for physical activities of athletes or fitness enthusiasts.
  •    Weight Organic compounds are used to increase body weight and change shape, so it is widely used by sportsmen to shape their body.
  •    Remedies - Steroids are used by athletes to cure their minor injuries or accidents because it has remedial effects.

Cons of Steroids:

    Any invention has side effects and risk involvement, so steroids also have side effects. These steroids boost the performance than standard capacity.

  •    Addiction If a person uses steroids daily then he became an addict of those because the chemical effects on his body, the steroids boost the working ability of body than natural capacity, so the person prefers to go for steroids further because he became used to with those organic compounds.
  •    Infertility The human body stops producing natural hormones, or it produces fewer hormones as compare to previous hormones when chemical hormones are uses too much so over usage of organic compound cause infertility.
  •    Health Steroids affect other body functions along with the purpose of their usage; they cause high cholesterol level, which increases the risk of heart diseases, high blood pressure, and over-weight.
  •    Withdrawal If a regular user of steroids wants to get rid of steroids and he stops using it suddenly, then the person may be feeling lazy, weak, depression, nausea, nervous break-down or body pains. Therefore, the natural body way of performance can change by a steroid.

What are Peptides?

      Peptides are protein in nature. They compile two or more amino acids which link together to form an amide. This linkage is covalent in the environment and formed between an amino acid (via a carboxyl group) and another amino acid (through nitrogen ending).

          The primary difference between protein and peptides lies in the altering number of amino acids. When two amino acids covalently bond, they will form dipeptides. Many multi proteins bond together they will be called as Polypeptide, which contains 10-50 amino acids residues are commonly known as peptides. The protein number can go up to 50.

         Most of the time, synthetic peptides we can see in the form of pharmaceutical products that includes some essential hormones as well as such as steroids, calcitonin, oxytocin, and adrenocorticotropic hormone. Based on various application and needs, the peptide has incurred multiple forms. Similarly, in different branches of biology, they are learning for different purposes.

         Such as in cell biology, when they bind on the base of the receptor, they develop a new form commonly called enzymes. Now, these natural forms can replace with synthetic ones — for instance, the drugs used for treating cancer.

       Some other uses of synthetic peptides have also come forward like they are used as reagents and standards in mass spectrometry (MS)-based applications. They play a vital role in terms of quantitation and characterization of proteins as well as biomarkers in many diseases. As far as the synthesis of peptides is concerned, they are significant for two ways of formation, solid-phase Fmoc peptide synthesis (SPPS) and liquid-phase peptide synthesis.

Peptide Bond:

     It is a chemical bond which formed when two molecules bind together in a way that the amino group of one molecule reacts with the carboxyl group of one molecule reacts and as a result, it releases one molecule of water (H2O). Due to the release of the water molecule, this reaction is called a condensation reaction or dehydration synthesis reaction. The bond of a carboxyl group and amino group together makes a relationship which calls a peptide bond, and the consequential molecule calls as an amide.

Types of Peptides:

      In this article, we will briefly discuss a few types of peptides which are given below:

  •    Dipeptides HGH Fragment:

          It formed because of the reaction between two amino acids forming one peptide bond. For example; Anserine (β-alanyl-N-methylhistidine) and Carnosine (β-alanyl-L-histidine).

  •     Tripeptides:

     This compound will form because of a reaction between 3 molecules of amino acids, and as a result, they will create 2 peptide bonds. For examples; Ophthalmic acid (L-γ-Glutamyl-α-L-amino butyral-glycine) and Glutathione (Glutamyl-cysteinyl-glycine)

  •    Oligopeptide: When amino acids in a range of 2-20 are chemically bonded through the peptide bond; as a result, the Oligopeptides will form. For example; Amanitin (Decapeptide) and Tetrapeptide; Tulfsin (threonine-lysine-proline-Arginine).
  •    Polypeptides When a peptide bond links more than 20 amino acids, the polypeptides will form — for example, Growth hormone and insulin.

Functions of Peptides:

Following are the features of the peptide in a human body:

  • Structural Functions In a human body, the main structure, formed of protein. Such as they compose the external membrane of every cell in the body, together they made human hair, skin, muscles, organs, and even tissues.
  • Driving Biochemical Reaction The essential items that run the biochemical reactions in a human body are enzymes. And enzymes are protein in nature. Enzymes act as a pacemaker in chemical reactions occurring in the human body. The most common examples are a chemical reaction in the nervous system, breathing, and digestion. Especially in terms of metabolism, where a series of biochemical reactions to convert food into energy.

Hormonal Regulation

  • Hormonal Regulation is the vital parts of the human body, which also make up of peptides. If a human body lacks the proper number of peptides in hormones it can even lead to severe cases such as puberty. They can even severely affect the other process, such as the production of sperm, menstrual cycle, and fertility in females. Other than this they are the determinants of the aging process, metabolism, regulate muscle mass, regulate moods and hair growth
  • Regulation of Cell Division either mitosis or meiosis, none can run with the peptides/protein deficiency. They replace the replenished cells and form new ones. There can be a different cause of cell damage such as exposure to the sun, chemical, and pollution. When a battery dies, the healthy one divides into two along with regulation through peptides. Upon a lack of protein leads to failure of cell growth, ultimately causing tumor growth and cancer.
  • Immune System Actions Antibodies are all, and all made up of peptide structure. They are highly essential for maintaining health and keeping the immune system healthy. Antibodies fight against virus and bacteria. Although the basic structure of the peptide in the antibody may differ, yet the presence of peptides. Antibody plays a communicative role, after detecting the invading germ the keep the immune system alert and helps to destroy the invader.

Pros of Peptides:

Let’s discuss a few general advantages f peptides:

  • Copies of the synthetic peptide can make easy for the human to fight against disease like cancer.
  • It has less percentage of toxicity as it lacks external proteins and nucleic acid.
  • Used in various anti-aging creams.
  • Best in use for anti-microbial treatments.
  • Essential component that forms the new skin at the place of disrupted one.
  • Helps to perform several essential body functions such as enzymes to speed up reactions, antibodies for the immune system, upon breakage produce water molecule in the body, hormones control the various functions even including sexual development in both males and females. All these functions are not possible without peptides.
  • Similar to nature peptides in a human body, science has reached levels where it can even synthesize the peptides in form or drugs as well as use them in the various diagnostic tool.

Cons of Peptides:

      Let’s discuss a few disadvantages of the peptides as well:

  • As it is a part of various types of cells such as T cell epitopes, so in their absence, they will adversely affect the system of elicit cell-mediated immunity (CMI).
  • Peptides may assume less immunogenic that compared to conventional as it causes inactivation of whole-virus vaccines.
  • It will require adjuvant, which means, a substance that a body needs to enhance the immune system.

          Steroids are synthetic drugs just like the natural hormones in the body.  AAS (Anabolic Androgenic Steroids) is the type of steroids, which copy the effect of male hormones and testosterone; used by people to build muscles and to increase strength. AAS are different from corticosteroids, which are medically used to treat asthma. There are more than one meaning of steroid. There is a medicine that's name is “steroid,” which people take to reel asthma and skin problems. Steroids help to reduce stress and increase the growth of the body.          Do you…

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Steroids

Mushroom Chitosan for Skin Care: A Plant-Based Option for Skincare

Published

4 days ago

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December 23, 2024

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Mushroom chitosan is a prominent ingredient in the skincare industry, celebrated for its compatibility with skin, moisturizing properties, and its role in wound healing and skin regeneration. Extracted from the cell walls of specific mushrooms, this eco-friendly, plant-based alternative to traditional chitosan (which is typically derived from shellfish) has recently gained considerable attention. It is swiftly becoming a favored ingredient in products designed to enhance skin texture, reduce inflammation, and improve moisture retention. This article delves into the science behind mushroom chitosan, its skin benefits, and how it compares to other popular ingredients.

Chitosan Overview

Chitosan is a natural polysaccharide traditionally obtained from the exoskeletons of shellfish like shrimp and crabs. However, mushroom chitosan, derived from fungi such as Aspergillus niger and Agaricus bisporus, offers a plant-based, vegan-friendly alternative. It provides similar benefits without the allergens or ethical concerns associated with animal-derived ingredients.

What It Does

Mushroom chitosan exhibits excellent biocompatibility, meaning it works well with human skin without causing irritation or allergic reactions. It is also biodegradable and sustainable, making it a particularly appealing option for eco-conscious consumers.

Mushroom chitosan forms a protective film on the skin’s surface, which helps retain moisture and shields the skin from environmental stressors like pollution and harmful bacteria. This barrier function also enhances the skin’s ability to retain water, making it especially beneficial for individuals with dry or sensitive skin.

Chitosan Magic

Additionally, chitosan has antimicrobial properties that can help prevent and treat skin infections. It promotes wound healing by accelerating the regeneration of skin cells, making it useful for post-inflammatory conditions like acne scars or minor cuts. Here is a summary of the main benefits of using mushroom chitosan:

Enhanced Hydration

Mushroom chitosan’s film-forming ability helps lock in moisture, maintaining the skin’s hydration levels. This is especially beneficial for dry, dehydrated skin or for maintaining a healthy moisture barrier.

Anti-inflammatory

Chitosan has been shown to reduce inflammation, which can soothe irritated or red skin. This makes it effective for people dealing with sensitive skin conditions like eczema or rosacea.

Chitosan Wound Healing and Skin Repair

Studies have shown that chitosan accelerates the skin’s natural healing process, making it a valuable ingredient for wound care and the recovery of damaged skin. It supports the regeneration of healthy skin cells, which can help minimize scarring and promote overall skin health.

Chitosan Antimicrobial Properties

Its ability to inhibit the growth of bacteria and fungi can help reduce breakouts and skin infections, providing a natural solution for acne-prone skin.

Anti-aging Benefits

Mushroom chitosan supports the skin’s elasticity and firmness by maintaining moisture levels and protecting it from oxidative stress, making it an effective anti-aging ingredient. By reducing the appearance of fine lines and improving texture, it contributes to a smoother, youthful complexion.

Related Article: Why A Newbie Must Use Electrolytes

Let's Compare it With Traditional Skin Products

Hyaluronic Acid: Mushroom chitosan and hyaluronic acid are both excellent for retaining moisture in the skin. However, chitosan also offers antimicrobial and wound-healing benefits, making it a multifunctional ingredient.

Collagen: Both ingredients aim to improve skin texture and elasticity. While collagen helps firm and plump the skin, mushroom chitosan focuses on moisture retention, repair, and protective qualities, offering a more comprehensive approach to skincare.

Traditional Chitosan: Mushroom chitosan has an edge over traditional shellfish-derived chitosan as it is plant-based and hypoallergenic. People with shellfish allergies can use it safely, and it’s also suitable for vegans and those seeking sustainable skincare options.

Main Products Containing Mushroom Chitosan

Moisturizers and Serums: As a potent humectant, mushroom chitosan is increasingly used in moisturizing products to boost skin hydration, enhancing the skin’s natural barrier.

Acne Treatments: Thanks to its antimicrobial and anti-inflammatory properties, mushroom chitosan is an excellent ingredient in acne-fighting formulas, reducing bacterial growth while calming inflamed skin.

Wound Healing Creams: Given its regenerative abilities, mushroom chitosan is often included in creams designed to speed up wound healing or reduce scarring, especially for acne-prone skin or post-skin procedures.

Anti-aging Products: Mushroom chitosan’s ability to retain moisture and support the skin’s elasticity makes it a key ingredient in anti-aging serums and creams, helping to reduce the appearance of fine lines and wrinkles.

Overall

Mushroom chitosan is an exciting, versatile ingredient in skincare that addresses multiple concerns, from hydration and inflammation to skin repair and protection. As a vegan-friendly, eco-conscious alternative to traditional chitosan, it offers a sustainable and effective solution for enhancing skin health. With its broad range of benefits and gentle nature, mushroom chitosan is poised to become a staple in modern skincare.

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Steroids

Glutathione – The Most Underrated Antioxidant

Published

2 weeks ago

on

December 10, 2024

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Glutathione, often referred to as the "Master Antioxidant," plays a crucial role in neutralizing free radicals and maintaining cellular health, making it an excellent supplement for bodybuilders across all age groups. Its ability to support liver detoxification, reduce inflammation, and enhance immune function is particularly beneficial for those undergoing intense training or using performance-enhancing drugs (PEDs).

Must Read: Human Chorionic Gonadotropin Hormone

As mentioned, it is a potent antioxidant that the body produces naturally. It plays a key role in detoxification, immune function, and maintaining cellular health.

How Can It Help You?

Glutathione neutralizes harmful free radicals, reducing oxidative stress and shielding cells from damage. This is especially critical for individuals using anabolic steroids or other PEDs, as these substances can increase oxidative stress, burden the liver, and hinder recovery.

Key Benefits of Glutathione Include

  • Liver Detoxification: Aids the liver in processing toxins, particularly those introduced by PED use.
  • Reduced Inflammation: Helps mitigate systemic inflammation, enhancing recovery and lowering injury risk.
  • Enhanced Immunity: Bolsters the immune system, keeping you healthier during intense training cycles.

Additionally, it supports skin health, reduces signs of fatigue, and promotes a general sense of well-being, making it invaluable for athletes focused on both performance and longevity.

How Is It Used?

Glutathione can be taken orally (in liposomal or reduced forms) or via injections for better bioavailability. A typical dose is 500–1000 mg daily if taken orally, or the same amount once a week if injected.

Are There Side Effects?

The hormone is usually well-tolerated. Rare side effects may include mild gastrointestinal discomfort or skin rashes, but these are uncommon. Injected glutathione is considered safe when properly administered.

Alternatives to Glutathione

There are several alternatives to glutathione that can help support your body's antioxidant defenses and overall health:

Vitamin C: This powerful antioxidant helps neutralize free radicals and can also help regenerate glutathione in the body.

Vitamin E: Another potent antioxidant that protects cell membranes from oxidative damage.

N-acetylcysteine (NAC): A precursor to glutathione, NAC can help boost the levels in the body.

Selenium: This trace mineral works synergistically with glutathione to enhance its antioxidant effects.

Milk Thistle: Known for its liver-protective properties, milk thistle can help support glutathione production.

Alpha-lipoic acid (ALA): This antioxidant helps regenerate other antioxidants, including glutathione, and can improve overall antioxidant capacity.

Curcumin: Found in turmeric, curcumin has strong anti-inflammatory and antioxidant properties.

Green Tea Extract: Rich in catechins, green tea extract provides powerful antioxidant benefits.

These alternatives can help maintain your body's antioxidant defenses and support overall health.

Legality of Glutathione Across Different Countries and Territories

The legality of glutathione supplements varies across different countries and territories. Here's a general overview:

United States

Glutathione supplements are widely available and legal in the U.S. They are regulated by the FDA under the Dietary Supplement Health and Education Act (DSHEA) of 19942. The FDA requires that supplements be labeled accurately and that they are safe for consumption.

Canada

In Canada, glutathione supplements are also legal and regulated by Health Canada. They must meet the Natural Health Products Regulations, ensuring safety, efficacy, and quality.

European Union

Glutathione supplements are legal in the EU and are regulated by the European Food Safety Authority (EFSA). They must comply with the EU's Novel Food Regulation if they are marketed as a new food product.

Australia

In Australia, glutathione supplements are legal and regulated by the Therapeutic Goods Administration (TGA). They must be listed on the Australian Register of Therapeutic Goods (ARTG) to be legally sold.

Japan

Its supplements are legal in Japan and are regulated by the Ministry of Health, Labour, and Welfare (MHLW). They must be approved as dietary supplements.

India

In India, glutathione supplements are legal and regulated by the Food Safety and Standards Authority of India (FSSAI). They must comply with the Food Safety and Standards (Food Products Standards and Food Additives) Regulations, 2011.

Other Countries

The legality of glutathione supplements can vary in other countries, and it's essential to check local regulations before purchasing or using them. Some countries may have stricter regulations or require specific approvals for dietary supplements.

Don't Miss: How to Manage Joint Stiffness While on AAS

It's always a good idea to consult with a healthcare professional or regulatory authority in your specific country to ensure compliance with local laws and regulations on the use of Glutathione.

Overall

By mitigating oxidative stress, glutathione helps in faster recovery, reducing injury risks, and promoting overall well-being. Additionally, its role in boosting skin health and combating fatigue adds to its appeal, contributing to both performance and longevity. However, it is essential for users to consult with healthcare professionals before starting any supplement regimen to ensure safety and efficacy, as individual needs and responses can vary. Glutathione's multifaceted benefits make it a valuable tool in the arsenal of bodybuilders aiming to optimize their health and performance.

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Bodybuilding

Top Video Games for Bodybuilders in 2024

Published

3 weeks ago

on

December 6, 2024

By

There are several video games that can be great for bodybuilders, combining fitness and fun! Here are some of the best options:

Ring Fit Adventure (Nintendo Switch)

The game uses the Ring-Con and Leg Strap to guide you through various exercises and adventures. It's a fun way to get a full-body workout while playing a game.

Fitness Boxing 2: VR Boxing Remastered (PlayStation VR)

It offers a full-body boxing workout with a variety of punches and combos. It's a great way to improve your fitness while enjoying a virtual boxing experience.

Must Read: Marvel-Inspired Training Clothing on Amazon 

Just Dance 2024

This popular dance game gets you moving to the beat with a variety of songs and dance routines. It's a fun way to burn calories and improve your coordination.

Zumba Fitness

Burn It Off (Nintendo Wii): This game offers a fun and energetic Zumba workout, perfect for those who enjoy dancing and want to get a good cardio workout.

Yoga for Beginners

If you're looking for a more relaxing workout, yoga games can help improve flexibility and reduce stress. Many of these games offer guided yoga sessions that you can follow along with.

Gym Tycoon

This game lets you build and manage your own gym, complete with various workout equipment and fitness classes. It's a great way to learn about different exercises and how to create effective workout routines.

The Sims 4: Fitness Stuff Pack

This expansion pack for The Sims 4 adds fitness equipment and activities to the game, allowing you to improve your character's fitness and join the athlete career.

Grand Theft Auto: San Andreas

While not a traditional fitness game, this classic game includes bodybuilding activities that can help your character gain muscle and improve fitness.

Knockout Home Fitness (Nintendo Switch)

This game offers a variety of boxing workouts that can help improve your strength and endurance.

Gym Simulator 24 (PC)

In this simulation game, you can build and manage your own fitness empire, creating workout routines and managing gym equipment.

Let's Get Fit (Nintendo Switch)

This game focuses on pure workouts, allowing you to set programs and follow along with digital trainers for a customized fitness experience.

Beat Saber (VR)

A popular VR game where you slash blocks to the beat of the music, providing an intense full-body workout.

Synth Riders (PlayStation VR)

This game combines freestyle dance and fitness, offering high-tempo tracks and multiplayer modes for a fun and energetic workout.

Yoga Master (PlayStation)

Designed by professional yoga coaches, this game offers a variety of yoga lessons and poses to improve flexibility and reduce stress.

Les Mills Bodycombat (PlayStation VR)

A martial arts-inspired workout game with a range of workout plans and coaching to keep you motivated.

OhShape Ultimate (PlayStation VR)

This game provides a full-body cardio workout with six sessions and two difficulty levels, designed to engage every part of your body.

These games offer a mix of cardio, strength, and flexibility workouts, making them great additions to your fitness routine.

Related Article: Supplemental Breast Milk for Bodybuilders 

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